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Batch Correction
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3
votes
3
replies
1.9k
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fastMNN based correction for large multi-run experiment requires a similar population set in all the individual datasets?
scrna-seq
integration
batch correction
updated 5.1 years ago by
Aaron Lun
★ 28k • written 5.1 years ago by
p.joshi
▴ 40
0
votes
1
reply
1.4k
views
Batch correction in Linear Models for methylation data
methylation
ComBat
Linear models
batch correction
AIC
updated 5.2 years ago by
Kevin Blighe
★ 4.0k • written 5.2 years ago by
lucasmiranda42
• 0
5
votes
3
replies
822
views
batch correction in DESeq2 > matrix not full rank > mitigate
DESeq2
batch correction
updated 5.3 years ago by
James W. MacDonald
68k • written 5.3 years ago by
MT
▴ 10
0
votes
3
replies
1.2k
views
Diffbind batch effect blocking error
Diffbind
ATAC
batch correction
blocking factor
updated 5.6 years ago by
Rory Stark
★ 5.2k • written 5.6 years ago by
rm1238
• 0
1
vote
1
reply
1.2k
views
All Pairwise Comparisons with DESeq2 While Controlling for Batch Effects: Does Reference Level Matter?
deseq2
differential expression
batch correction
design
updated 5.7 years ago by
Michael Love
43k • written 5.7 years ago by
wunderl
▴ 40
4
votes
4
replies
1.8k
views
Batch Correction: DESeq2 Linear Model vs Batch-Correction-Specific Algorithms (RUV, ComBat, ect.)
deseq2
differential expression
batch correction
updated 5.7 years ago by
Michael Love
43k • written 5.7 years ago by
wunderl
▴ 40
4
votes
5
replies
2.2k
views
Using SC3 with batch corrected MNN values
SC3
Scater
Scran
scRNA-Seq
Batch Correction
updated 5.9 years ago by
Vladimir Kiselev
▴ 150 • written 5.9 years ago by
hamza_karakurt
▴ 60
7 results • Page
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Comment: how many significant figures are there in DESeq2 output
by
ATpoint
★ 4.7k
If you want consistency then use a fixed software environment like Docker, wirh fixed code and thresholds that make sense. Rounding to near…
Comment: Compare TCGA-PAAD with GTEx gene expression
by
Jane
• 0
why aren't there any answers?
Comment: Too many significant genes when integrating gtex and tcga
by
Jane
• 0
I encountered the same issue: too many DEGs after limma analysis. It is sad that until today we can still see the paper published where GTE…
Comment: how many significant figures are there in DESeq2 output
by
Matthew McCormack
▴ 180
Thank you for your reply. It is good to know that cutoff of 0.05 means less than 0.05. My concerns are about consistency and reproducibili…
Comment: DiffBind edgeR normalization --- why are the normalization factors all equal to
by
ATpoint
★ 4.7k
No, normalization factors from edgeR rather than size factors from DESeq2 are not proportional, it's a different concept and implementation…
Votes
A: Unbalanced experiment with multiple samples from each patient.
Unbalanced experiment with multiple samples from each patient.
Answer: Vertical line at A=0, nothing else, on MA plot
Answer: GSVA Error Code "Calling gsva(expr=., gset.idx.list=., method=., ...) is defunct
Answer: Group-specific condition effects with individuals nested: matrix is not full ra
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